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September 2022; 1 (1) Research ArticleOpen Access

Curriculum Innovations: Virtual Didactics as a Tool for Harmonizing Education About Rare Topics in Neuroimmunology

John Peters, Jeffrey A. Cohen, John R. Corboy, Sarah E. Hopkins, Le H. Hua, Mihir Kakara, Derek McFaul, Ahmed Z. Obeidat, Vijayshree Yadav, Erin E. Longbrake
First published October 7, 2022, DOI: https://doi.org/10.1212/NE9.0000000000200008
John Peters
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Jeffrey A. Cohen
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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John R. Corboy
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Sarah E. Hopkins
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Le H. Hua
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Mihir Kakara
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Derek McFaul
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Ahmed Z. Obeidat
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Vijayshree Yadav
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Erin E. Longbrake
From the Department of Neurology (J.P., E.E.L.), Yale School of Medicine, New Haven, CT; Department of Neurology (J.A.C.), Mellen MS Center, Neurological Institute, Cleveland Clinic, OH; Rocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus (J.R.C.), University of Colorado, Denver; Division of Neurology (S.E.H.), Children's Hospital of Philadelphia, University of Pennsylvania; Mellen Program for Multiple Sclerosis (L.H.H.), Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV; Department of Neurology (M.K.), University of Pennsylvania Perelman School of Medicine, Philadelphia; Department of Neurology (D.M., V.Y.), Oregon Health & Science University, Portland; and Department of Neurology (A.Z.O.), Medical College of Wisconsin, Milwaukee.
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Citation
Curriculum Innovations: Virtual Didactics as a Tool for Harmonizing Education About Rare Topics in Neuroimmunology
John Peters, Jeffrey A. Cohen, John R. Corboy, Sarah E. Hopkins, Le H. Hua, Mihir Kakara, Derek McFaul, Ahmed Z. Obeidat, Vijayshree Yadav, Erin E. Longbrake
Neurol Edu Sep 2022, 1 (1) e200008; DOI: 10.1212/NE9.0000000000200008

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    Figure Trainees' Average Comfort Levels Across All Topics Improved After the Seminar Series: (A) All Trainees, (B) First-Year Fellows Only, and (C) Second-Year (and Beyond) Fellows Only

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    Table 1

    Demographic Information

    Percentage of respondents to precourse survey (n = 72)Percentage of respondents to postcourse survey (n = 26)
    Level of training
     Resident18.111.5
     First-year fellow56.953.8
     Second-year (or beyond) fellow25.034.6
    No. of trainees at respondent's institution
     127.123.0
     220.319.2
     422.019.2
     4 or more30.538.4
    Geographic location of training program
     Northeast United States39.042.3
     Southeast United States5.13.8
     Midwest United States27.119.2
     Southwest United States11.93.8
     West United States16.930.8
    • View popup
    Table 2

    Weighted Averages Preseries and Postseries for Individual Topics

    TopicPreseries-weighted average of trainee comfort level (n = 72, scale 1–5)Postseries-weighted average of trainee comfort level (n = 26, scale 1–5)Preseries-weighted average of program director expected value (n = 22, scale 1–5)Postseries-weighted average of program director impression of educational value (n = 12, scale 1–5)
    Advanced MRI techniques for MS/neuroinflammation2.743.774.554.2
    Anti-NMDA receptor encephalitis and mechanisms of disease3.384.124.594.45
    Autoimmune myelitis and its mimics3.324.124.774.55
    B-cell and autoantibody-mediated pathogenesis in CNS autoimmunity3.094.04.824.36
    Basic science of remyelination2.533.584.364.1
    Clinical trial design2.553.424.754.27
    Emerging autoimmune diseases2.883.854.734.6
    Ethnicity and diversity in the MS experience2.923.814.414.45
    Hematopoietic and mesenchymal stem-cell therapy for MS2.313.544.434.09
    Immunobiology of MS2.933.854.824.44
    Integrative medicine and cannabis2.543.424.183.6
    Lab techniques and tools for understanding antibody-mediated diseases2.613.654.54.45
    Neurorheumatology: Neurosarcoidosis, CNS vasculitis, CNS lupus, neuro-Beçhet's2.783.844.824.64
    Pediatric MS2.743.734.554.4
    PML and opportunistic infections3.123.964.554.5
    Progressive MS: challenges in finding and demonstrating effective therapies3.24.124.734.42
    Symptomatic management of advanced MS3.534.274.643.8
    Urological issues and their management in MS2.613.734.414.4
    • Abbreviations: MS = multiple sclerosis; PML = progressive multifocal leukoencephalopathy.

    • View popup
    Table 3

    Qualitative Feedback From Trainees and Program Directors

    ThemeExample quotes
    Benefits of interactions with leading expertsThe lectures are fantastic and it is great to hear from the speakers themselves. Excited to be able to participate myself.
    Improvement on prior approaches for learning niche and cross-disciplinary topicsWonderful seminar series. Love the concept of topics that may not be core topics at each institution or universal.
    Overall, I thought the series was very useful, particularly in covering topics other than MS DMTs.
    Opportunities for live and asynchronous participationThis was an excellent resource during the MS fellowship, especially the on-demand videos which could be watched at a later time.
    Areas for growthAllow more time for discussion—many sessions went over time and it would be great to allow for more engagement.
    • Abbreviations: DMT = disease-modifying therapy; MS = multiple sclerosis.

  • NameLocationContribution
    John Peters, MDDepartment of Neurology, Yale School of Medicine, New Haven, CTDrafting/revision of the manuscript for content, including medical writing for content; major role in the acquisition of data; study concept or design; analysis or interpretation of data
    Jeffrey A. Cohen, MDDepartment of Neurology, Mellen MS Center, Neurological Institute, Cleveland Clinic, OHDrafting/revision of the manuscript for content, including medical writing for content; study concept or design
    John R. Corboy, MD, MARocky Mountain Multiple Sclerosis Center at Anschutz Medical Campus, University of Colorado, DenverDrafting/revision of the manuscript for content, including medical writing for content; study concept or design
    Sarah E. Hopkins, MS, MSPHDivision of Neurology, Children's Hospital of Philadelphia, University of PennsylvaniaDrafting/revision of the manuscript for content, including medical writing for content; study concept or design
    Le H. Hua, MDMellen Program for Multiple Sclerosis, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NVDrafting/revision of the manuscript for content, including medical writing for content; study concept or design
    Mihir Kakara, MBBSDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, PhiladelphiaDrafting/revision of the manuscript for content, including medical writing for content
    Derek McFaul, DODepartment of Neurology, Oregon Health & Science University, PortlandDrafting/revision of the manuscript for content, including medical writing for content
    Ahmed Z. Obeidat, MD, PhDDepartment of Neurology, Medical College of Wisconsin, MilwaukeeDrafting/revision of the manuscript for content, including medical writing for content; study concept or design
    Vijayshree Yadav, MD, MCRDepartment of Neurology, Oregon Health & Science University, PortlandDrafting/revision of the manuscript for content, including medical writing for content; study concept or design
    Erin E. Longbrake, MD, PhDDepartment of Neurology, Yale School of Medicine, New Haven, CTDrafting/revision of the manuscript for content, including medical writing for content; major role in the acquisition of data; study concept or design; analysis or interpretation of data

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